American Journal of Science Education Research | Review Article                                                                                           

Modulating the T Helper 17 Cell/Regulatory T Cell Balance: Roles of Natural Compounds and Cellular Therapies

*Correspondence: Sining Wang*

DOI: https://doi.org/10.71010/2835-6764/ajser-e301

Published: 26 January, 2026

Abstract
T cells play important roles in the adaptive immune system. Among them, T helper 17 cells promote inflammation, while regulatory T cells maintain immune tolerance. Imbalance between these two subsets is commonly found in autoimmune and chronic inflammatory diseases. Recent studies have identified plant compounds Bergapten, Salidroside and Gegen Qinlian Decoction could act as potential regulators in several disease models, while cellular immunotherapies, including CAR-engineered Treg therapy and Breg cell expansion therapies, have already been used in preclinical and early clinical studies. This review will summarize and analyze emerging and current strategies.
Keywords: Th17, Treg, autoimmune diseases, inflammation, immune balance.
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Cite this article

Wang S (2026) Modulating the T Helper 17 Cell/Regulatory T Cell Balance: Roles of Natural Compounds and Cellular Therapies. American J Sci Edu Re: AJSER-301. https://doi.org/ 10.71010/2835-6764/ajser-e301.
Received Date: 10 January, 2026; Accepted Date: 19 January, 2026; Published Date: 26 January, 2026


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